L Glutamine and Weight Loss

L glutamine (also referred to simply as glutamine) is the most abundant non-essential amino acid in the body. It is found primarily in skeletal muscle and the bloodstream. In fact, muscle tissue is considered a reservoir of l-glutamine since 60 percent of the free-floating amino acids in muscle tissue are l-glutamine.

L glutamine has a variety of functions. When it is required by various tissues of the body, particularly the gut, immune system and certain organs (brain, kidneys, pancreas, gall bladder and liver), it is released by the skeletal muscle, which results in catabolism (breakdown) of muscle tissue.

L glutamine is known as a 'conditionally essential' amino acid because under certain conditions (intense exercise, stress, disease, burns, etc.) the body requires greater than normal levels of it.


From a weight loss perspective l-glutamine is an enormously beneficial supplement. Since it is the most abundant free-floating amino acid in muscle tissue it can be easily depleted from the muscles when other tissues and organs of the body require it. This, of course, has a catabolic effect on the muscle tissue from which it has been released. Supplementing with l-glutamine powder will therefore keep muscle levels of this amino acid high and will therefore prevent its depletion from muscle tissue.

It has also been shown that supplementing with l-glutamine powder will increase the rate of protein and glycogen synthesis in muscle tissue. Increasing protein synthesis in muscle tissue will help to boost the metabolism and therefore make the body a more efficient fat-burner. Promoting glycogen synthesis will ensure the muscles have plenty of energy to draw from during exercise. This effect also increases cell volumisation (water in cells), which leads to a further boost of the metabolism.

Supplementing with l-glutamine has also been shown to directly boost growth hormone (GH) secretion in the body and GH is the most powerful fat-burning and anti-ageing hormone in the body.

Here's some of the glutamine benefits:

  • Causes a substantial increase in growth hormone (GH) production. A 2-gram oral dose has been shown to increase GH production fourfold.

  • Maintains proper cellular hydration or cell volume (anabolic effect).

  • Is a building block for your body's most powerful antioxidant, glutathione, which is made from l-glutamine, cysteine and glycine.

  • Helps muscle glycogen deposition.

  • Is an integral part of muscle metabolism.

  • Has an anti-catabolic effect, which means it prevents the breakdown of muscle.
  • Recommended Use of L Glutamine

    10 grams of l-glutamine a day is recommended. The best time to take it is after a workout, with dinner or before bed.

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