What Does Cortisol Do ?What does cortisol do? This is a common question people ask because weight gain and cortisol are so closely related. A simple answer is that the purpose of cortisol is as a stress hormone in the body and its primary purpose is to breakdown body tissues to be used as an energy source. Whenever the body is put under stress, no matter whether it is psychological stress or physical stress, the body responds by producing cortisol. Cortisol is released from the cortex (outer portion) of the adrenal glands and is sent into the bloodstream. It targets the liver, muscles, skin, adipose tissue and lymphatic system. In the liver it promotes ‘gluconeogenesis’, which is the creation of glucose from amino acids (protein) and glycerol (the backbone of triglycerides). In the muscles it promotes the breakdown of lean tissue to liberate amino acids. These amino acids then go to the liver to go through the process of gluconeogenesis, which will raise the blood sugar (glucose) level . In the skin cortisol promotes vasoconstriction, which is constriction of the blood vessels. This is an evolutionary response whereby if we are ever faced with a physical conflict, if we are cut we are less likely to bleed excessively because of the restricted blood flow to the skin. In the adipose tissue, cortisol promotes the breakdown of fats into fatty acids and glycerol. The glycerol may then be sent to the liver to contribute to gluconeogenesis and raise blood sugar levels. Cortisol is also known to suppress immune responses in many body tissues, especially inflammatory responses. Overall, from a weight loss perspective it is important to keep cortisol in check. Since one of its primary functions is to raise glucose levels in the blood stream, it also contributes to insulin resistance. Plus, the loss of muscle that results from its production and therefore, the resulting metabolism depression far outweigh the fat breakdown that occurs. Finally, cortisol is a steroid hormone, which means it comes from the same basic compound as other steroid hormones in the body, pregnenolone. Since the body produces a limited amount of pregnenolone, if it is used for cortisol production, less is left over for the other steroid hormones that have potent fat-burning abilities. In saying all this, it is important not to have cortisol too low either because a small amount is required for optimum thyroid functioning. Overall, this article should answer the question of what does cortisol do ?
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